struct   let major_contigs_b37 =     List.init 22 (fun i -> sprintf "%d" (i + 1))     @ ["X""Y""MT";]   let major_contigs_hg_family =     List.init 22 (fun i -> sprintf "chr%d" (i + 1))     @ [       "chrX";       "chrY";       "chrM";     ]   let major_contigs_mm10 =     List.init 19 (fun i -> sprintf "%d" (i + 1))     @ [ "X""Y" ]   module Name = struct     let b37 = "b37"     let b37decoy = "b37decoy"     let b38 = "b38"     let hg38 = "hg38"     let hg18 = "hg18"     let hg19 = "hg19"     let mm10 = "mm10"   end   (* Used by both B37 and B37decoy *)   let b37_dbsnp_url =     "https://storage.googleapis.com/hammerlab-biokepi-data/raw_data/dbsnp_138.b37.vcf.gz"   let b37_cosmic_url =     "http://www.broadinstitute.org/cancer/cga/sites/default/files/data/tools/mutect/b37_cosmic_v54_120711.vcf"   let b37_exome_gtf_url =     "http://ftp.ensembl.org/pub/release-75/gtf/homo_sapiens/Homo_sapiens.GRCh37.75.gtf.gz"   let b37_cdna_url =     "http://ftp.ensembl.org/pub/release-75/fasta/homo_sapiens/cdna/Homo_sapiens.GRCh37.75.cdna.all.fa.gz"   let b37_whess_url =     "ftp://genetics.bwh.harvard.edu/pph2/whess/polyphen-2.2.2-whess-2011_12.sqlite.bz2"   let b37_known_indels_url =     "https://storage.googleapis.com/hammerlab-biokepi-data/raw_data/Mills_and_1000G_gold_standard.indels.b37.vcf.gz"   let human = "homo sapiens"   let mouse = "mus musculus"   let b37 =     create Name.b37       ~species:human       ~ensembl:75       ~metadata:"Provided by the Biokepi library"       ~major_contigs:major_contigs_b37       ~fasta:Location.(           url "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/2.8/b37/human_g1k_v37.fasta.gz"           |> gunzip)       ~dbsnp:Location.(url b37_dbsnp_url |> gunzip)       (* Alternate?          "ftp://ftp.ncbi.nlm.nih.gov/snp/organisms/human_9606/VCF/v4.0/00-All.vcf.gz"       *)       ~known_indels:Location.(url b37_known_indels_url |> gunzip)       ~cosmic:Location.(url b37_cosmic_url)       ~exome_gtf:Location.(url b37_exome_gtf_url |> gunzip)       ~cdna:Location.(url b37_cdna_url |> gunzip)       ~whess:Location.(url b37_whess_url |> bunzip2)       ~snpeff_name:"GRCh37.75"   let b37decoy =     create Name.b37decoy       ~species:human       ~ensembl:75       ~metadata:"Provided by the Biokepi library"       ~major_contigs:major_contigs_b37       ~fasta:Location.(           url             "ftp://ftp.1000genomes.ebi.ac.uk/vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz"           |> gunzip)       ~dbsnp:Location.(url b37_dbsnp_url |> gunzip)       ~known_indels:Location.(url b37_known_indels_url |> gunzip)       ~exome_gtf:Location.(url b37_exome_gtf_url |> gunzip)       ~cosmic:Location.(url b37_cosmic_url)       ~cdna:Location.(url b37_cdna_url |> gunzip)       ~whess:Location.(url b37_whess_url |> bunzip2)       ~snpeff_name:"GRCh37.75"   let hg38 =     (* Release 87 *)     let hg38_url =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/hg38/hg38bundle/Homo_sapiens_assembly38.fasta.gz" in     let dbsnp_hg38 =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/hg38/hg38bundle/Homo_sapiens_assembly38.dbsnp.vcf.gz" in     let known_indels_hg38 =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/hg38/hg38bundle/Homo_sapiens_assembly38.known_indels.vcf.gz" in     create Name.hg38       ~species:human       ~ensembl:87       ~metadata:"Provided by the Biokepi library"       ~major_contigs:major_contigs_hg_family       ~fasta:Location.(url hg38_url|> gunzip)       ~dbsnp:Location.(url dbsnp_hg38 |> gunzip)       ~known_indels:Location.(url known_indels_hg38 |> gunzip)       ~snpeff_name:"GRCh38.86"   let b38 =     (* Release 87 *)     let b38_url =       "http://ftp.ensembl.org/pub/release-87/fasta/homo_sapiens/dna/Homo_sapiens.GRCh38.dna.primary_assembly.fa.gz" in     let gtf_b38_url =       "http://ftp.ensembl.org/pub/release-87/gtf/homo_sapiens/Homo_sapiens.GRCh38.87.gtf.gz" in     let cdna_b38_url =       "http://ftp.ensembl.org/pub/release-87/fasta/homo_sapiens/cdna/Homo_sapiens.GRCh38.cdna.all.fa.gz" in     let dbsnp_url =       "http://ftp.ncbi.nlm.nih.gov/snp/organisms/human_9606_b150_GRCh38p7/VCF/common_all_20170710.vcf.gz" in     create Name.b38       ~species:human       ~ensembl:87       ~metadata:"Provided by the Biokepi library"       ~major_contigs:major_contigs_b37       ~fasta:Location.(url b38_url |> gunzip)       ~exome_gtf:Location.(url gtf_b38_url |> gunzip)       ~dbsnp:Location.(url dbsnp_url |> gunzip)       ~cdna:Location.(url cdna_b38_url |> gunzip)       ~snpeff_name:"GRCh38.86"   let hg18 =     let hg18_url =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/2.8/hg18/Homo_sapiens_assembly18.fasta.gz" in     let dbsnp_hg18_url =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/2.8/hg18/dbsnp_138.hg18.vcf.gz" in     create Name.hg18       ~ensembl:54       ~species:human       ~metadata:"Provided by the Biokepi library"       ~major_contigs:major_contigs_hg_family       ~fasta:Location.(url hg18_url|> gunzip)       ~dbsnp:Location.(url dbsnp_hg18_url |> gunzip)   let hg19 =     let hg19_url =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/2.8/hg19/ucsc.hg19.fasta.gz" in     let dbsnp_hg19_url =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/2.8/hg19/dbsnp_138.hg19.vcf.gz" in     let known_indels_hg19_url =       "ftp://gsapubftp-anonymous@ftp.broadinstitute.org/bundle/2.8/hg19/Mills_and_1000G_gold_standard.indels.hg19.sites.vcf.gz" in     create Name.hg19       ~ensembl:75       ~species:human       ~metadata:"Provided by the Biokepi library"       ~major_contigs:major_contigs_hg_family       ~fasta:Location.(url hg19_url|> gunzip)       ~dbsnp:Location.(url dbsnp_hg19_url |> gunzip)       ~known_indels:Location.(url known_indels_hg19_url |> gunzip)       ~whess:Location.(url b37_whess_url |> bunzip2)       ~snpeff_name:"hg19"   let mm10 =     let mm10_url =       "https://storage.googleapis.com/hammerlab-biokepi-data/raw_data/mm10.GRCm38.dna_sm.fa" in     let dbsnp_mm10_snps_url =       "ftp://ftp-mouse.sanger.ac.uk/REL-1303-SNPs_Indels-GRCm38/mgp.v3.snps.rsIDdbSNPv137.vcf.gz" in     let dbsnp_mm10_indels_url =       "ftp://ftp-mouse.sanger.ac.uk/REL-1303-SNPs_Indels-GRCm38/mgp.v3.indels.rsIDdbSNPv137.vcf.gz" in     let gene_annotations_gtf =       "ftp://ftp.ensembl.org/pub/release-84/gtf/mus_musculus/Mus_musculus.GRCm38.84.gtf.gz" in     let cdna_mm10_url =       "ftp://ftp.ensembl.org/pub/release-84/fasta/mus_musculus/cdna/Mus_musculus.GRCm38.cdna.all.fa.gz" in     create Name.mm10       ~ensembl:87       ~species:mouse       ~metadata:"Provided by the Biokepi Library"       ~major_contigs:major_contigs_mm10       ~fasta:Location.(url mm10_url |> gunzip)       ~dbsnp:Location.(           vcf_concat ["db_snps.vcf", url dbsnp_mm10_snps_url |> gunzip;                       "db_indels.vcf", url dbsnp_mm10_indels_url |> gunzip]         )       ~exome_gtf:Location.(url gene_annotations_gtf |> gunzip)       ~cdna:Location.(url cdna_mm10_url |> gunzip)       ~snpeff_name:"mm10" end