let default ~host ~run_program ~install_path () =    Machine.Tool.Kit.of_list [     create_python_tool ~host ~run_program ~install_path       ~version:"1.1.0" (Pip, Package_PyPI "pyensembl");     create_python_tool ~host ~run_program ~install_path       ~version:"0.1.2" (Pip, Package_PyPI "vcf-annotate-polyphen");     create_python_tool ~host ~run_program ~install_path       ~version:"0.1.3" ~check_bin:"isovar-protein-sequences.py"       (Pip, Package_PyPI "isovar");     create_python_tool ~host ~run_program ~install_path       ~version:"0.1.2" (Pip, Package_PyPI "topiary");     create_python_tool ~host ~run_program ~install_path       ~version:"0.4.2" (Pip, Package_PyPI "vaxrank");    ]