let isovar       ?(configuration=Tools.Isovar.Configuration.default)       vcf bam =     let v = get_vcf (AF.get_file vcf) in     let b = get_bam (AF.get_file bam) in     let reference_build =       if v#product#reference_build = b#product#reference_build       then v#product#reference_build       else         ksprintf failwith "VCF and Bam do not agree on their reference build: bam: %s Vs vcf: %s"           b#product#reference_build v#product#reference_build     in     let output_file =       Name_file.in_directory ~readable_suffix:"isovar.csv" Config.work_dir [         Tools.Isovar.Configuration.name configuration;         reference_build;         (Filename.chop_extension (Filename.basename v#product#path));         (Filename.chop_extension (Filename.basename b#product#path));       ] in     Isovar_result (       Tools.Isovar.run ~configuration ~run_with ~reference_build         ~vcf:v ~bam:b ~output_file     )     |> AF.with_provenance "isovar" ["vcf", AF.get_provenance vcf;                                     "bam", AF.get_provenance bam]       ~string_arguments:[         "reference-build", reference_build;         "configuration-name", Tools.Isovar.Configuration.name configuration;       ]       ~json_arguments:[         "configuration", Tools.Isovar.Configuration.to_json configuration;       ]